Naproxen
Also known as: Aleve, All Day Pain, All Day Pain Relief, All Day Pain Rlf, All Day Relief, Anaprox, Naprelan, Naprosyn, Wal-Proxen.
Wholesale (NADAC) cost for every strength and dosage form — the price pharmacies pay, published weekly by CMS. Not your out-of-pocket price.
Wholesale (NADAC) prices — every strength & form
| Strength | Form | NADAC / unit | Class |
|---|---|---|---|
| 125 MG/5 ML | (unspecified) | $0.176 / mL | Generic |
| 220 MG | Tablet OTC | $0.066 / unit | Generic |
| 220 MG | Capsule OTC | $0.149 / unit | Generic |
| 250 MG | Tablet | $0.047 / unit | Generic |
| 275 MG | Tablet | $0.173 / unit | Generic |
| 375 MG | Tablet | $0.057 / unit | Generic |
| 375 MG | Tablet DR | $2.34 / unit | Generic |
| 500 MG | Tablet | $0.063 / unit | Generic |
| 500 MG | Tablet DR | $1.93 / unit | Generic |
| 500 MG | Tablet CR | $9.36 / unit | Generic |
| 500 MG | Tablet ER | $9.36 / unit | Generic |
| 550 MG | Tablet | $0.223 / unit | Generic |
Wholesale (NADAC) — the price pharmacies pay, not your out-of-pocket price. Liquids, creams, and sprays are priced per mL or gram; a typical package may be a bottle or tube (size not set yet).
NADAC week of 2026-07-01 · updated weekly · source CMS
Medicaid & Medicare spending · 2024
In 2024, Medicaid paid $36,014,742 gross for Naproxen across 2,831,214 prescriptions (measured, national).
Medicare Part D EST spent an estimated ~$36,534,643 gross (retail pharmacy only; excludes Part B).
Gross program spending, before rebates — not what patients pay out of pocket. Brand net cost is materially lower after confidential rebates; generics are close to net.
Source: Medicaid SDUD 2024 · Medicare Part D 2024 · CMSBuy it with a cash program — no insurance needed
500 MG · Tablet CR
TrumpRx discount card$156.04 · 30 tablets — $307.58 · 60 tablets — $459.11 · 90 tablets
Cost Plus Drugs (mail)$193.36 · 30 tablets — $376.47 · 60 tablets — $559.57 · 90 tablets
Amazon Pharmacy (mail)$198.50 · 30 tablets — $396.50 · 60 tablets — $594.50 · 90 tablets
Fixed program prices at participating pharmacies or by mail. Covered strengths & quantities only; program terms apply. TrumpRx card & mail-order prices as listed on trumprx.gov (updated weekly). Mail orders take days to arrive.