Methylprednisolone

Also known as: Depo-Medrol, Medrol, Methylprednisolone Ss, Solu-Medrol.

Wholesale (NADAC) cost for every strength and dosage form — the price pharmacies pay, published weekly by CMS. Not your out-of-pocket price.

Wholesale (NADAC) prices — every strength & form

StrengthFormNADAC / unitPackageClass
4 MG(unspecified)$0.112 / unitGeneric
4 MGTablet$0.124 / unitGeneric
8 MGTablet$1.02 / unitGeneric
16 MGTablet$1.37 / unitGeneric
32 MGTablet$2.91 / unitGeneric
40 MG/MLVial$8.12 / mL†Generic
40 MGVial$6.30 / unit†Brand
80 MG/MLVial$11.80 / mL†Generic
125 MG(unspecified)$4.04 / unitGeneric
125 MGVial$9.88 / unit†Brand
400 MG/10 ML(unspecified)$5.81 / mLGeneric
Wholesale (NADAC) — the price pharmacies pay, not your out-of-pocket price. Brand list prices fall after confidential rebates. † Package size not curated yet — priced per single unit/mL, not per full pen, inhaler, or vial. Liquids, creams, and sprays are priced per mL or gram; a typical package may be a bottle or tube (size not set yet).
NADAC week of 2026-07-01 · updated weekly · source CMS

Medicaid & Medicare spending · 2024

In 2024, Medicaid paid $30,795,791 gross for Methylprednisolone across 2,084,903 prescriptions (measured, national).

Medicare Part D EST spent an estimated ~$42,466,488 gross (retail pharmacy only; excludes Part B).

Gross program spending, before rebates — not what patients pay out of pocket. Brand net cost is materially lower after confidential rebates; generics are close to net.

Source: Medicaid SDUD 2024 · Medicare Part D 2024 · CMS
Buy it with a cash program — no insurance needed
8 MG · Tablet
TrumpRx discount card$54.64 · 90 tablets
Amazon Pharmacy (mail)$55.40 · 90 tablets
Cost Plus Drugs (mail)$73.51 · 90 tablets
32 MG · Tablet
TrumpRx discount card$42.20 · 30 tablets$83.90 · 60 tablets$125.60 · 90 tablets
Amazon Pharmacy (mail)$42.20 · 30 tablets$83.90 · 60 tablets$125.60 · 90 tablets
Cost Plus Drugs (mail)$72.35 · 30 tablets$134.45 · 60 tablets$196.55 · 90 tablets
Fixed program prices at participating pharmacies or by mail. Covered strengths & quantities only; program terms apply. TrumpRx card & mail-order prices as listed on trumprx.gov (updated weekly). Mail orders take days to arrive.

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