Methotrexate
Also known as: Otrexup, Rasuvo, Trexall.
Wholesale (NADAC) cost for every strength and dosage form — the price pharmacies pay, published weekly by CMS. Not your out-of-pocket price.
Wholesale (NADAC) prices — every strength & form
| Strength | Form | NADAC / unit | Package | Class |
|---|---|---|---|---|
| 2.5 MG | Tablet | $0.163 / unit | — | Generic |
| 5 MG | Tablet | $24.09 / unit | — | Brand |
| 7.5 MG/0.15 ML | Auto-injector | $960.29 / mL† | — | Brand |
| 7.5 MG | Tablet | $36.21 / unit | — | Brand |
| 10 MG/0.2 ML | Auto-injector | $721.81 / mL† | — | Brand |
| 10 MG | Tablet | $48.21 / unit | — | Brand |
| 12.5 MG/0.25 ML | Auto-injector | $574.87 / mL† | — | Brand |
| 15 MG/0.3 ML | Auto-injector | $482.29 / mL† | — | Brand |
| 17.5 MG/0.35 ML | Auto-injector | $409.93 / mL† | — | Brand |
| 20 MG/0.4 ML | Auto-injector | $361.03 / mL† | — | Brand |
| 25 MG/0.4 ML | Auto-injector | $475.81 / mL† | — | Brand |
| 25 MG/0.5 ML | Auto-injector | $288.38 / mL† | — | Brand |
| 50 MG/2 ML | Vial | $1.74 / mL† | — | Generic |
| 250 MG/10 ML | Vial | $2.00 / mL† | — | Generic |
Wholesale (NADAC) — the price pharmacies pay, not your out-of-pocket price. Brand list prices fall after confidential rebates. † Package size not curated yet — priced per single unit/mL, not per full pen, inhaler, or vial.
NADAC week of 2026-07-01 · updated weekly · source CMS
Medicaid & Medicare spending · 2024
In 2024, Medicaid paid $18,893,784 gross for Methotrexate across 513,785 prescriptions (measured, national).
Medicare Part D EST spent an estimated ~$58,114,301 gross (retail pharmacy only; excludes Part B).
Gross program spending, before rebates — not what patients pay out of pocket. Brand net cost is materially lower after confidential rebates; generics are close to net.
Source: Medicaid SDUD 2024 · Medicare Part D 2024 · CMS