Acetaminophen / Diphenhydramine

Also known as: Acetadryl, Acetaminophen PM, PM Pain Rlf, Pain Reliever PM, Pain Rlf PM, Panadol PM, Tylenol PM.

Wholesale (NADAC) cost for every strength and dosage form — the price pharmacies pay, published weekly by CMS. Not your out-of-pocket price.

Wholesale (NADAC) prices — every strength & form

StrengthFormNADAC / unitClass
25-500 MGTablet OTC$0.045 / unitGeneric
25-500 MG(unspecified) OTC$0.045 / unitGeneric
500-25 MG(unspecified) OTC$0.045 / unitGeneric
Tablet OTC$0.045 / unitGeneric
Softgel OTC$0.045 / unitGeneric
Wholesale (NADAC) — the price pharmacies pay, not your out-of-pocket price.
NADAC week of 2026-07-01 · updated weekly · source CMS

Medicaid & Medicare spending · 2024

In 2024, Medicaid paid $18,628 gross for Acetaminophen / Diphenhydramine across 2,053 prescriptions (measured, national).

Gross program spending, before rebates — not what patients pay out of pocket. Brand net cost is materially lower after confidential rebates; generics are close to net.

Source: Medicaid SDUD 2024 · Medicare Part D 2024 · CMS

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